David Coulthard's Red Bull-Renault will carry a special one-off livery for the Scot's final grand prix in Brazil this weekend.
The car's usual Red Bull colours are to be replaced by a white-based scheme promoting the work of the Wings for Life charity, which supports people who have suffered spinal cord injuries.
“I'm dedicating my last race to the vision of making paraplegia curable,” said Coulthard.
“In Formula 1 success is determined by a few seconds, in medicine people think in terms of years.
But in both disciplines, ambition and commitment are crucial factors that are needed in order to reach the finishing line as soon as possible.
"Wings for Life helps to accelerate the breakthrough in spinal cord research.”
Although F1 rules require teams to run identical liveries on both cars, Red Bull has received approval from its rivals to run the alternative colours on Coulthard's car because of its charitable purpose.
"Currently there is very little government funding for this type of research and the pharmaceutical companies are not interested, of course, as you can't buy a pill to cure spinal cord injury," the Scot continued.
"It was founded by Dietrich Mateschitz who obviously is the founder of Red Bull and Heinz Kinigadner whose son suffered a spinal cord injury in a motorbike accident.
"All of the money that is raised through public donations goes to fund various institutions throughout the world and works with other foundations, like the Christopher Reeve Foundation, to find a cure for spinal cord injuries."